The Happytime Murders is a 2018 American adult puppet buddy cop crime comedy film directed by Brian Henson and written by Todd Berger from a story by Berger and Dee Austin Robertson. The film stars Melissa McCarthy, Bill Barretta, Joel McHale, Maya Rudolph, Leslie David Baker, and Elizabeth Banks. Set in a world where humans and living puppets co-exist, the film follows a puppet private investigator and a human police detective who must solve a murder spree of retired sitcom stars.

The film was first announced in 2008 by The Jim Henson Company, the production studio of Muppets creator Jim Henson. Various actors, including Cameron Diaz, Katherine Heigl and Jamie Foxx, were approached to star before McCarthy signed on in May 2017. Filming began in Los Angeles that September, and involved the use of over 120 puppets. The Happytime Murders was the first film released by Henson Alternative, a banner of The Jim Henson Company aimed toward adult audiences.

The Happytime Murders was released on August 24, 2018, by STXfilms. It received mostly negative reviews from critics for its humor, performances and story, though the puppetry received praise. The film was a box-office bomb, grossing $27.5 million worldwide against a $40–47 million budget. The film received six nominations at the 39th Golden Raspberry Awards, including Worst Picture, and Worst Actress for McCarthy who won that award.