Great Balls of Fire! is a 1989 American biographical drama film directed by Jim McBride and starring Dennis Quaid as rockabilly pioneer Jerry Lee Lewis. Based on a biography by Myra Lewis and Murray M. Silver Jr., the screenplay is written by McBride and Jack Baran. The film is produced by Adam Fields, with executive producers credited as Michael Grais, Mark Victor, and Art Levinson.

The film depicts the early career of Lewis, from his rise to rock-and-roll stardom to his controversial marriage to his 13-year-old cousin that led to his downfall. Until the scandal of the marriage depreciated his image, many had thought Lewis would supplant Elvis Presley as the "King of Rock and Roll" in the 1950s.