The Equation of Love and Death (Chinese: 李米的猜想; pinyin: lǐ mǐ de cāi xiǎng; lit. 'Li Mi's Supposition') is a 2008 Chinese dramatic film written and directed by Cao Baoping and starring Zhou Xun. The film is a Chinese (Huayi Brothers) and Hong Kong (Sundream Motion Pictures) co-production. It is Cao's second solo feature after 2006's Trouble Makers.

The Equation of Love and Death premiered in China on September 18, 2008 in Shanghai and had its North American premiere at the 2008 Vancouver International Film Festival where it was part of the Dragons and Tigers side competition.The Equation of Love and Death tells the story of Li Mi (played by Zhou Xun), a Kunming cab driver who longs for the day she can be reunited with her missing boyfriend. After a case of mistaken identity, a kidnapping, and a threat of extortion, Li Mi's dream may be on the cusp of becoming a reality.