She Done Him Wrong is a 1933 pre-Code American crime/comedy film starring Mae West and Cary Grant, directed by Lowell Sherman. The plot includes melodramatic and musical elements, with a supporting cast featuring Owen Moore, Gilbert Roland, Noah Beery Sr., Rochelle Hudson, and Louise Beavers. The film was adapted from the successful 1928 Broadway play Diamond Lil by Mae West. The film is famous for West's many double entendres and quips, including her best-known "Why don't you come up sometime and see me?". She Done Him Wrong was a box-office success and the film was nominated for the Academy Award for Best Picture.

In 1996, She Done Him Wrong was selected for preservation in the United States National Film Registry by the Library of Congress as being "culturally, historically, or aesthetically significant".