Alice in Wonderland is a 2010 American dark fantasy adventure film directed by Tim Burton from a screenplay written by Linda Woolverton and produced by Walt Disney Pictures. The film stars Mia Wasikowska in the title role, with Johnny Depp, Anne Hathaway, Matt Lucas, Helena Bonham Carter, and Crispin Glover, while featuring the voices of Alan Rickman, Stephen Fry, Michael Sheen, and Timothy Spall. A live-action adaptation and re-imagining of Lewis Carroll's works, the film follows Alice Kingsleigh, a nineteen-year-old who accidentally falls down a rabbit hole, returns to Wonderland, and alongside the Mad Hatter helps restore the White Queen to her throne by fighting against the Red Queen and her Jabberwocky, a dragon that terrorizes Wonderland's inhabitants.

Alice in Wonderland began development in December 2007, when Burton was asked to direct two 3D films for Disney, including the remake of Frankenweenie. Production began in September 2008 and concluded within three months, and was shot in the United Kingdom and the United States. It was followed by an extensive post-production and visual effects process where filming included live-action and motion-capture sequences. Burton's frequent collaborator Danny Elfman composed an original theme for the film, which premiered in London at the Odeon Leicester Square on February 25, 2010, and was released in the United Kingdom and the United States through the Disney Digital 3D, RealD 3D, and IMAX 3D formats as well as in conventional theaters on March 5.

The film generated over $1.025 billion in ticket sales and became the fifth highest-grossing film during its theatrical run, and it is also the second-highest-grossing film of 2010. Amongst Disney's live-action adaptations, the film is tied for third-most-expensive, alongside Mulan, and fourth-highest-grossing readaptation to date. It received three nominations at the 68th Golden Globe Awards, including Best Motion Picture – Musical or Comedy. At the 83rd Academy Awards, it won Best Art Direction and Best Costume Design, and was also nominated for Best Visual Effects, while the film received numerous other accolades.

While not the first such film in its genre, Alice in Wonderland is credited with starting a trend of live-action fairy tale and fantasy films being green-lit, particularly from Walt Disney Studios. A follow-up film, titled Alice Through the Looking Glass, was released on May 27, 2016.