Rushing Roulette is a 1965 Warner Bros. Merrie Melodies cartoon directed by Robert McKimson. The short was released on July 31, 1965, and stars Wile E. Coyote and the Road Runner. It was the second Road Runner cartoon directed by someone other than Chuck Jones, who had almost exclusively used the characters since their debut in 1949 (the first was 1965's The Wild Chase, directed by Friz Freleng). McKimson directed one other Road Runner cartoon the following year, Sugar and Spies.

Unlike the ten Rudy Larriva-directed Road Runner shorts after Run, Run, Sweet Road Runner (which featured a series of pre-recorded music cues that didn't follow the action on-screen as closely), Rushing Roulette featured an entirely original score by Bill Lava.

The title of the cartoon is a play on Russian roulette.