Amanda Knox: Murder on Trial in Italy (also known as The Amanda Knox Story)

is a 2011 American true crime television film. It stars Hayden Panettiere as Amanda Knox, Paolo Romio as Raffaele Sollecito, Djibril Kébé as Rudy Guede and Amanda Fernando Stevens as Meredith Kercher, and first aired on the Lifetime network on February 21, 2011.

Set between 2007 and 2009, Amanda Knox: Murder on Trial in Italy is based on the murder of Meredith Kercher in Perugia, Italy, and the subsequent trials of the suspects, Guede, Knox and Sollecito. It was written by Wendy Battles, who has worked on scripts for the American television series CSI: NY and Law & Order, and filmed in Rome, after officials refused to grant the production team permission to shoot in Perugia. The film contains a re-enactment of the murder. In Italy, the television film has been transmitted on Canale 5, on December 3, 2012, after Amanda Knox sent a team of lawyers to Mediaset, to prevent the airing.

After its first broadcast, the film was followed by a one-hour documentary, Beyond the Headlines: Amanda Knox, which examines the Italian judicial system and includes interviews with the parents and friends of Knox, investigators, prosecutors and legal scholars.