Prophecy is a 1979 American science fiction monster horror-thriller film directed by John Frankenheimer and written by David Seltzer. It stars Robert Foxworth, Talia Shire and Armand Assante. Set along the Androscoggin or Ossipee River, the film follows an environmental agent and his wife filing a report on a paper mill in the river, not knowing that the paper mill's waste has polluted the river, causing mutations to man and beast alike. One of these animals, a local bear, runs amok in the wilderness.

A novelization of the film, written by Seltzer as well, was also published, with the tagline "A Story of Unrelenting Terror".