The Human Centipede 2 (Full Sequence) is a 2011 psychological body horror film written, directed, and co-produced by Tom Six. An international co-production of the Netherlands and the United States, and the sequel to Six's 2009 film The Human Centipede (First Sequence), the film stars Laurence R. Harvey as a psychiatrically and intellectually impaired English man who watches and becomes obsessed with the first Human Centipede film, and decides to make his own "centipede" consisting of 12 people by using crude and violent techniques to connect their lips to each others buttocks, including Ashlynn Yennie, an actress from the first film.

The Human Centipede 2 (Full Sequence) received substantial attention and controversy for its graphic depictions of violence, sexual violence, forced defecation, and overall body horror. It was subject to heavy censorship throughout the world where it was sometimes edited to remove objectionable content or banned altogether. It was critically panned, with much criticism focused on its acting, plot, editing, and violence, although Harvey's performance received some praise from critics.