Innocent Blood (also known in some regions as A French Vampire in America) is a 1992 American black comedy horror film directed by John Landis and written by Michael Wolk. The film stars Anne Parillaud as a beautiful French vampire who finds herself pitted against a gang of mobsters led by Salvatore Macelli (Robert Loggia) who eventually becomes a vampire and schemes to build a criminal syndicate of vampires.

The film is set in and was filmed in Pittsburgh, Pennsylvania. Actors Tony Sirico, Tony Lip, and David Proval have supporting parts as gangsters, foreshadowing their roles in The Sopranos. It also features early appearances by Anthony LaPaglia, Angela Bassett, and Chazz Palminteri. The film is notable for being a mixture of the vampire, gangster and buddy cop genres. The film was a box-office bomb, earning only $5 million over its $20 million budget.