Attack of the Killer Tomatoes is a 1978 American parody film produced by J. Stephen Peace and John DeBello, and directed by John DeBello based upon an original idea by Costa Dillon. The film stars David Miller, George Wilson, Sharon Taylor, and Jack Riley.

The screenplay was written by Dillon, Peace, and DeBello. The film spoofs B movies and was made on a budget of less than $100,000. The story involves tomatoes becoming sentient by unknown means and revolting against humanity.

Critical reception of Attack of the Killer Tomatoes was mostly negative. The box office success of the film led to three sequels, all co-written by the same three writers and directed by DeBello.