Duck Amuck is an American animated surreal comedy short film directed by Chuck Jones and written by Michael Maltese. The short was released on February 28, 1953, as part of the Merrie Melodies series, and stars Daffy Duck.

In the cartoon, Daffy Duck is tormented by an unseen, mischievous animator, who constantly changes Daffy's locations, clothing, voice, physical appearance, and even shape, much to Daffy's aggravation, embarrassment, and finally rage. Pandemonium reigns throughout the cartoon as Daffy attempts to steer the action back to some kind of normality, only for the animator to either ignore him or, more frequently, to over-literally interpret his increasingly frantic demands. In the end, the tormenting animator is revealed to be Bugs Bunny.

In 1994, it was voted #2 of The 50 Greatest Cartoons of all time by members of the animation field, behind only What's Opera, Doc?, also directed by Jones and written by Maltese. In 1999, Duck Amuck was added to the National Film Registry for being "culturally, historically, or aesthetically significant."

The short inspired the 2007 Nintendo DS game Looney Tunes: Duck Amuck.