Mysteries of Lisbon (Portuguese: Mistérios de Lisboa) is a 2010 Portuguese period drama film directed by Chilean filmmaker Raúl Ruiz based on an 1854 novel of the same name by Camilo Castelo Branco. The movie's running time is 272 minutes. It played as a miniseries in 60-minute installments in some countries. The film has won nine awards and been nominated for eight more.

The plot of Mysteries of Lisbon is rich with coincidences, plot twists, multiple narrators, disguises, and flashbacks-within-flashbacks. Every major character possesses at least two identities, and the story—which hopscotches around Europe in the late 18th and early 19th centuries—is set against the Napoleonic Wars and includes pirates, a woman hellbent on avenging the death of her twin brother, and at least four different love triangles. Above all, Mysteries of Lisbon is about the mechanics of storytelling and imagination.