The 2006 SummerSlam was the 19th annual SummerSlam professional wrestling pay-per-view (PPV) event produced by World Wrestling Entertainment (WWE). It was held for wrestlers from the promotion's Raw, SmackDown!, and ECW brand divisions. The event took place on August 20, 2006, at the TD Banknorth Garden in Boston, Massachusetts. This marked the first inter-brand pay-per-view to include the ECW brand.

The main match on the Raw brand featured Edge against John Cena for the WWE Championship, which Edge won by pinfall after hitting Cena in the back of the head with a pair of brass knuckles. The main match on the SmackDown! brand pitted King Booker against Batista for the World Heavyweight Championship, which Batista won by disqualification following interference from Queen Sharmell. The primary match on the ECW brand pitted Big Show against Sabu in an Extreme rules match for the ECW World Championship. Big Show won the match and retained the title after pinning Sabu following a chokeslam through a table. The undercard included D-Generation X (DX) (Triple H and Shawn Michaels) against Vince and Shane McMahon as well as Hulk Hogan against Randy Orton, which was Hogan's last match in WWE.

Several of the existing feuds carried on after the event. D-Generation X continued feuding with The McMahons, defeating them and The Big Show in a Hell in a Cell match the following month. The feud between Batista and King Booker also continued, with the two facing off as part of a fatal four-way match at No Mercy, which Booker won. The following month, at Unforgiven, John Cena defeated Edge in a Tables, Ladders, and Chairs match to win the WWE Championship and conclude their storyline.