Tarzan's Greatest Adventure is a 1959 American Eastmancolor adventure film directed by John Guillermin, produced by Sy Weintraub and Harvey Hayutin, and written by Les Crutchfield, based on the character created by Edgar Rice Burroughs as the twenty-second film of the Tarzan film series that began with 1932's Tarzan the Ape Man. With a strong supporting cast that included Anthony Quayle and Sean Connery, and a focus on action and suspense, the film won critical praise as a Tarzan film that appealed to adults as well as children.

The film features a literate Tarzan portrayed by Gordon Scott. The character of Jane, Tarzan's wife, does not appear and is not mentioned. At one point, Tarzan briefly romances a female character, suggesting that he is a loner, not a family man. Cheeta, Tarzan's chimp companion in many films, appears only a few times near the start of the film, and the kind of comic relief that Cheeta represents is generally absent from the film. Released on July 8, 1959, was followed by Tarzan the Magnificent in 1960.