Frankenstein is a 2004 American science fiction horror television film produced and directed by Marcus Nispel and written by John Shiban. It is a loose adaptation of Mary Shelley's Frankenstein, and stars Parker Posey as a police detective on the trail of a serial killer, played by Thomas Kretschmann, in present-day New Orleans. The detective is aided in her search by one of the killer's creations, played by Vincent Perez. Adam Goldberg, Ivana Miličević and Michael Madsen co-star. It was produced by Lions Gate Films, and aired on the USA Network on October 10, 2004.

The film was intended as the pilot for an ongoing series, and was initially based on Dean Koontz's version of Frankenstein. USA and the producers decided that major changes must be made and Koontz had no interest in the show in its new form. He withdrew from association with it and turned to the task of realizing the original concept of the book form. Subsequently, executive producer Martin Scorsese also expressed desire to exit the series. Koontz later developed the concept into a series of five novels: Frankenstein: Prodigal Son, Frankenstein: City of Night, Frankenstein: Dead and Alive, Frankenstein: Lost Souls, and Frankenstein: The Dead Town.