The 2012 Sacrifice was a professional wrestling pay-per-view (PPV) event produced by the Total Nonstop Action Wrestling (TNA) promotion, which took place on May 13, 2012 at the Impact Wrestling Zone in Orlando, Florida. It was the eighth under the Sacrifice chronology and fifth event in the 2012 TNA PPV schedule.

In the main event, Bobby Roode defeated Rob Van Dam in a Ladder match to retain the TNA World Heavyweight Championship. Other matches that preceded the final bout were Kurt Angle defeating A.J Styles, Austin Aries defeating Bully Ray, and Crimson defeating Eric Young, all in a singles match. Also, Devon defeated Robbie E and Robbie T to retain his TNA Television Championship, Gail Kim defeated Brooke Tessmacher to retain her TNA Women's Knockout Championship, and Christopher Daniels and Kazarian defeated Samoa Joe and Magnus to win the TNA World Tag Team Championship.

In October 2017, with the launch of the Global Wrestling Network, the event became available to stream on demand.