Mexican Spitfire's Blessed Event is a 1943 American comedy film directed by Leslie Goodwins and written by Charles E. Roberts and Dane Lussier. It is the sequel to the 1942 film Mexican Spitfire's Elephant. The film stars Lupe Vélez, Leon Errol, Walter Reed, Elisabeth Risdon, Lydia Bilbrook and Hugh Beaumont. The film was released on July 17, 1943, by RKO Pictures.

This was the eighth and final film in the series. It marks the penultimate screen appearance for Lupe Vélez, who committed suicide on 14 Dec 1944 after completing one more feature in her native Mexico.