8 Heads in a Duffel Bag is a 1997 black comedy film starring Joe Pesci, Kristy Swanson and David Spade. It was the directorial debut of screenwriter Tom Schulman. The film was a box office disappointment and received negative reviews from critics.

The film initially focuses on a wiseguy who has been tasked with transporting a cargo of severed heads to a crime boss. The duffel bag with the heads is switched with that of a young tourist heading for Mexico. The young man and his girlfriend soon look for ways to get rid of the heads, while the wiseguy attempts to find replacement heads at a cryonics lab.