Master Minds is a 1949 American comedy horror film by Monogram Pictures. It is the sixteenth film in The Bowery Boys series.

In the film, a man gains the ability of precognition. He uses it perform at a sideshow carnival. He is soon kidnapped by a mad scientist who wants to use him in a brain transplantation experiment. The man's brain is scheduled to be transferred into the scientist's version of Frankenstein's monster.