U Me Aur Hum (transl. You, Me, and Us) is a 2008 Indian Hindi-language romantic drama film co-written, directed, and produced by Ajay Devgn. The film tells the story of Ajay (Devgn), who meets barmaid Piya (Kajol) on a cruise with his friends (Sumeet Raghavan, Divya Dutta, Karan Khanna, and Isha Sharvani). They fall in love and marry; a few months later, Piya is diagnosed with Alzheimer's disease.

The film was announced in May 2007 and was the directorial debut of Devgn, who had long wanted to direct a film. He wrote the story, and the screenplay was written by Robin Bhatt, Sutanu Gupta, and Akash Khurana. Principal photography, by Aseem Bajaj, began in India shortly after the film was announced. It was edited by Dharmendra Sharma, and the background score was written by Monty Sharma. The soundtrack was composed by Vishal Bhardwaj, with lyrics by Munna Dhiman.

U Me Aur Hum was released on 11 April 2008. Made on a budget of ₹220 million (US$2.5 million), it grossed ₹400.2 million (US$4.6 million) worldwide. Critical response to the film was mixed; its performances (particularly those of Devgn and Kajol) were praised, but Devgn's direction and the film's climax were criticized. U Me Aur Hum received several nominations, including Best Actress for Kajol at the Filmfare and Screen Awards.