I Am Legend is a 2007 American post-apocalyptic action thriller film directed by Francis Lawrence from a screenplay by Akiva Goldsman and Mark Protosevich and starring Will Smith as US Army virologist Robert Neville. Loosely based on the 1954 novel of the same name by Richard Matheson, the film is set in New York City after a virus, which was originally created to cure cancer, has wiped out most of mankind, leaving Neville as the last human in New York, other than nocturnal mutants. Neville is immune to the virus, and he works to develop a cure while defending himself against the hostile mutants. It is the third feature-film adaptation of Matheson's novel following 1964's The Last Man on Earth and 1971's The Omega Man.

Warner Bros. began developing I Am Legend in 1994 and various actors and directors were attached to the project, though production was delayed due to budgetary concerns related to the script. Production began in 2006 in New York City, filming mainly on location in the city, including a $5 million scene at the Brooklyn Bridge.

I Am Legend was released on December 14, 2007, in the United States and Canada. It opened to the largest-ever box office (not adjusted for inflation) for a non-Christmas film released in the U.S. in December and was the seventh-highest-grossing film of 2007, earning $256 million domestically and $329 million internationally for a total of $585 million. The film received generally positive reviews, with Smith's performance being singled out for praise, while criticism focused on its divergences from the novel, particularly the ending. In 2022, a sequel was revealed to be in development, with Smith set to reprise his role as Neville and co-produce the film with Michael B. Jordan, who will also have a starring role.