The 2022 Worlds Collide was the third Worlds Collide professional wrestling livestreaming event produced by WWE. While the event was held primarily for wrestlers from the promotion's NXT and NXT UK brand divisions, Worlds Collide also featured some wrestlers from WWE's main roster brands, Raw and SmackDown. It took place on Sunday, September 4, 2022, at the WWE Performance Center in Orlando, Florida, and was the first Worlds Collide to livestream on Peacock. This was the first Worlds Collide event since 2020 and also the final event for NXT UK, which will relaunch as NXT Europe in 2023. This was also NXT's last major event in which the brand was referred to as "NXT 2.0", as nine days later, the "2.0" moniker was dropped.

Seven matches were contested at the event, including two dark matches that were later streamed on Level Up. All five matches that took place at the actual event were interbrand championship matches and three saw all but one of NXT UK's championships unified into their respective NXT championship counterparts. In the main event, NXT Champion Bron Breakker defeated NXT United Kingdom Champion Tyler Bate to unify both championships. In other prominent matches, NXT Women's Champion Mandy Rose defeated NXT UK Women's Champion Meiko Satomura and Blair Davenport in a triple threat match to unify both women's championships, and Pretty Deadly (Elton Prince and Kit Wilson) defeated NXT Tag Team Champions The Creed Brothers (Brutus Creed and Julius Creed), NXT UK Tag Team Champions Brooks Jensen and Josh Briggs, and Gallus (Mark Coffey and Wolfgang) in a fatal four-way tag team elimination match to unify both tag team championships. The NXT UK Heritage Cup was the only championship between the two brands that was not defended at the event and it was later transferred to NXT in April 2023.