Mark of the Vampire is a 1935 American horror film directed by Tod Browning, and starring Lionel Barrymore, Elizabeth Allan, Bela Lugosi, Lionel Atwill, and Jean Hersholt, produced by Metro Goldwyn Mayer. Its plot follows a series of deaths and attacks by vampires that brings eminent expert Professor Zelen to the aid of Irena Borotyn, who is about to be married. Her father, Sir Karell, died from complete loss of blood, with bite wounds on his neck, and it appears he may be one of the undead now plaguing the area.

It has been described as a talkie remake of Browning's silent London After Midnight (1927), though it does not credit the older film or its writers.