Mark of the Vampire (also known as Vampires of Prague) is a 1935 American horror film, starring Lionel Barrymore, Elizabeth Allan, Bela Lugosi, Lionel Atwill, and Jean Hersholt, and directed by Tod Browning. A series of deaths and attacks by vampires brings the eminent expert Professor Zelen to the aid of Irena Borotyn, who is about to be married. Her father, Sir Karell, died from complete loss of blood, with bite wounds on his neck, and it appears he may be one of the undead now plaguing the area.

It has been described as a talkie remake of Browning's silent London After Midnight (1927), though it does not credit the older film or its writers.