Operation Petticoat is a 1959 American World War II submarine comedy film in Eastmancolor from Universal-International, produced by Robert Arthur, directed by Blake Edwards, and starring Cary Grant and Tony Curtis.

The film tells in flashback the misadventures of a fictional U.S. Navy submarine, USS Sea Tiger, during the Battle of the Philippines in the opening days of the United States involvement in World War II. Some elements of the screenplay were taken from actual incidents that happened with some of the Pacific Fleet's submarines during the war. Members of the cast include several actors who went on to become television stars in the 1960s and 1970s: Gavin MacLeod of The Love Boat and McHale's Navy, Marion Ross of Happy Days, and Dick Sargent of Bewitched.

Paul King, Joseph Stone, Stanley Shapiro, and Maurice Richlin were nominated for the Academy Award for Best Writing for their work on Operation Petticoat. The film was the basis for a TV series in 1977 starring John Astin in Grant's role.