45 Minutes From Hollywood is a 1926 American two-reel silent comedy film directed by Fred Guiol and released by Pathé Exchange. The film's runtime is 15 minutes.

At the time, it was known as a Glenn Tryon vehicle, but today it is best remembered as the second instance of Stan Laurel and Oliver Hardy appearing in the same film together — although they do not share any scenes — at least half a decade after their first chance billing in The Lucky Dog (1921).

As the film uses footage from the Theda Bara star vehicle Madame Mystery (released April 1926, featuring Hardy in the supporting cast, and co-written and co-directed by Laurel), it is also the last screen appearance of silent film vamp Bara.