The 2016 NXT TakeOver: Toronto was the 12th NXT TakeOver and inaugural TakeOver: Toronto professional wrestling livestreaming event produced by WWE. It was held exclusively for wrestlers from the promotion's NXT brand division. The event aired exclusively on the WWE Network and took place on November 19, 2016, at the Air Canada Centre in Toronto, Ontario, Canada as part of that year's Survivor Series weekend. It was the second NXT TakeOver held outside of the United States, after TakeOver: London in December 2015.

Five matches were contested at the event. In the main event, Samoa Joe defeated Shinsuke Nakamura to win the NXT Championship and became the first man to hold the title twice. It was also Mickie James's return to WWE for one night only in NXT.