Pardon the Interruption (abbreviated PTI) is an American sports talk television show that airs weekdays on various ESPN TV channels. It is hosted by Tony Kornheiser and Michael Wilbon, who discuss, and frequently argue over, the top stories of the day in "sports... and other stuff" (as Kornheiser put it in the show's original promo). For thirteen years Tony Reali also appeared as the statistician and correcting errors that Mike and Tony made.

Similar in format to Gene Siskel and Roger Ebert's At the Movies, PTI is known for its playful banter between the cohosts, humorous and often loud tone, and a "rundown" graphic which lists the topics yet to be discussed on the right-hand side of the screen. The show's popularity has led to the creation of similar shows on ESPN and similar segments on other series, and the rundown graphic has since been implemented on the morning editions of SportsCenter, among many imitators.