Political Animals is a six-episode American comedy drama miniseries created by Greg Berlanti. The series aired in the United States on USA Network from July 15 through August 19, 2012. Sigourney Weaver portrays Elaine Barrish, a divorced former First Lady and Governor of Illinois, as well as the current Secretary of State. Weaver and the show's production team acknowledge that the lead character has some similarities to Hillary Clinton. They say that the premise of the show is "very much about all families who have been in the White House, the price they've paid for being there and the fact that those same families will often try or continue to try to get back into the White House again."

While it was speculated that the miniseries would lead into a full season, on November 2, 2012, USA Network announced their decision to stick with their initial plan of producing it as a miniseries.