John Safran vs God is an eight-part television documentary series by John Safran which was broadcast on SBS TV of Australia in 2004. It has been described in a media release as "John Safran's most audacious project yet". It had a much more serious tone than Safran's previous work Music Jamboree. The show was released by Ghost of Your Ex-Boyfriend Productions and SBS Independent, was co-written with Mark O'Toole, directed by Craig Melville, and produced by Richard Lowenstein, Selin Yaman, and Ghost Pictures. The production team was known as Ghost of Your Ex-Boyfriend Productions, an amalgamation of John Safran's Ex-Boyfriend Productions, and Richard Lowenstein's Ghost Productions. The series won the 2005 Australian Film Institute Award for Best Comedy Series.

The show's opening theme is "Hate Priest" by the band Mozart on Crack. The opening sequence features John in a black suit breaking out of a patch of black scorched earth with his bare hands during a thunderstorm. The words of Revelation 20:7, "when the thousand years are over Satan will be released from his prison", are spoken in a low pseudo-ominous voice.