The Amber Ruffin Show is an American comedy late-night talk show. Produced by Universal Television and Sethmaker Shoemeyers Productions and starring Amber Ruffin, it features a mix of sketches and monologues. The series was ordered for nine half-hour episodes and premiered on NBCUniversal's video-streaming service Peacock on September 25, 2020. Peacock ordered an additional 10 episodes in December 2020, and the series was promoted with a brief run on the NBC broadcast network in February and March 2021. The third season premiered on September 30, 2022. In 2023, it was announced the program would only return on occasion as specials but these were never ordered.

The first season received nominations from the Primetime Emmy Awards, TCA Awards, and the Critics' Choice Television Awards, among others. The second season which premiered on October 8, 2021 received nominations from the TCA Awards, GLAAD Media Awards and the Critics' Choice Television Awards, among others.