Megas XLR is an American animated television series created by Jody Schaeffer and George Krstic for Cartoon Network. The series revolves around two slackers: mechanic Coop and his best friend Jamie, who find a mecha robot from the future called MEGAS (Mechanized Earth Guard Attack System) in a Jersey City, New Jersey junkyard. Coop modifies Megas and replaces his head, the control center, with a classic muscle car, and names him XLR (eXtra Large Robot). Together with Megas's original pilot Kiva, they must defend Earth from the evil alien race called "the Glorft". The series is an homage and parody of mecha anime. Krstic was originally one of the co-creators of MTV's Downtown.

Schaeffer and Krstic conceived the idea of an animated series where the main character would pilot a giant robot utilizing his video gaming skills. The pilot episode, LowBrow, was shown in 2002 during Cartoon Network's Cartoon Cartoon Weekend Summerfest, to determine which pilot would become a new Cartoon Cartoon; it was the most popular among viewers. It aired on the Toonami block from May 1, 2004, to January 15, 2005, for two seasons (totaling 26 episodes), before being cancelled due to low ratings.

Despite low ratings, the series was met with positive reception, and was ranked at No. 4 on ToonZone's "Toons of the 2000s: Top 5 Cartoon Network Originals". There have been various fan efforts and petitions to revive the show since its cancellation.

Megas XLR was produced by Cartoon Network Studios; Titmouse, Inc. animated the main title and did animation work on Season 1.