Angels & Demons is a 2009 American mystery thriller film directed by Ron Howard and written by Akiva Goldsman and David Koepp. It is based on Dan Brown's 2000 novel of the same title. A sequel to the 2006 film The Da Vinci Code, also directed by Howard, it is the second installment in the Robert Langdon film series; however, the novel version was published before The Da Vinci Code novel.

Filming took place in Rome, Italy, and the Sony Pictures Studios in Culver City, California. Tom Hanks reprises his role as Professor Robert Langdon, while Ayelet Zurer stars as Dr. Vittoria Vetra, a CERN scientist joining Langdon in the quest to recover a missing vial of antimatter from a mysterious Illuminati terrorist. Producer Brian Grazer, composer Hans Zimmer and screenwriter Akiva Goldsman also return, with Koepp coming on board to help the latter.

Angels and Demons premiered in Rome on May 4 2009, and was released on May 15, by Sony Pictures Releasing throught the Columbia Pictures banner. It grossed $485.9 million worldwide against a $150 million production budget, becoming the ninth highest-grossing film of 2009, and received mixed reviews from critics, who considered it an improvement over its predecessor. A sequel, titled Inferno, concluded the series in 2016.