Killer Crocodile is a 1989 Italian horror film directed by Fabrizio De Angelis (credited as Larry Ludman), who co-wrote the screenplay with Dardano Sacchetti (as David Parker Jr.). It stars Anthony Crenna, Ann Douglas, Thomas Moore, Wohrman Williams and Van Johnson. The film's plot centers around a group of ecologists who, while investigating the illegal dumping of hazardous waste in a swamp, encounter an enormous, man-eating crocodile.

The film was shot back-to-back with a sequel, Killer Crocodile 2 (1990).