Homeward Bound II: Lost in San Francisco is a 1996 American adventure comedy film and the sequel to the 1993 film Homeward Bound: The Incredible Journey directed by David R. Ellis. The film features the three pets from the first film, Shadow the Golden Retriever (voiced by Ralph Waite, replacing Don Ameche after the latter's death in 1993), Sassy the Himalayan cat (Sally Field), and Chance the American Bulldog (Michael J. Fox). It also features the voice work of Sinbad, Carla Gugino, Tisha Campbell-Martin, Stephen Tobolowsky, Jon Polito, Adam Goldberg, Al Michaels, Tommy Lasorda and Bob Uecker. In addition, Robert Hays, Kim Greist, Veronica Lauren, Kevin Chevalia and Benj Thall reprised their roles for the sequel.

The movie was met with mixed critical reception overall, while it fared better with audiences. The film was released on March 8, 1996, and went on to gross over $32 million at the box office.