Marquis de Sade: Justine (a.k.a. Deadly Sanctuary) (Italian: Justine ovvero le disavventure della virtù) is a 1969 drama film directed by Jesús Franco. The film is based on the 1791 novel Justine by the Marquis de Sade. The film is set in 1700s France where Justine (Romina Power) and her sister Juliette (Maria Rohm) are orphans in Paris. Juliette becomes a prostitute and marries a rich noble. Justine is falsely arrested and sentenced to death, then escapes from prison to become a fugitive.

The film had Franco's largest budget to date, of just under a million dollars. Franco originally wanted to cast Rosemary Dexter as Justine, but was forced to cast Romina Power in the role, which led to Franco changing the story to suit her.