Quarantine 2: Terminal is a 2011 American horror film and a sequel to the 2008 film, Quarantine. It was written and directed by John Pogue and produced by Marc Brienstock. The film stars Mercedes Mason, Josh Cooke and Mattie Liptak as passengers on an airplane where the mutant rabies virus from the previous film is now spreading, forcing the plane to make an emergency landing at a terminal that is promptly surrounded by the government, trapping the passengers and crew as they search for answers and a means of escape.

Although the first film was a remake of the Spanish film REC, Quarantine 2 has no relation to any of the REC films and has an entirely different plot and setting. The film received mixed reviews from critics.