Mouse Wreckers is a 1949 Warner Bros. Looney Tunes short directed by Chuck Jones, written by Michael Maltese and starring Hubie and Bertie in their first pairing with the redesigned Claude Cat (an early, primordial version of the cat appeared in 1943's The Aristo-Cat). The cartoon was released on April 23, 1949.The short centers around Hubie and Bertie's attempts to move into a new home by chasing Claude out of the house. Mel Blanc voices Bertie and an uncredited Stan Freberg voices Hubie. The title is a pun on house wrecker or home wrecker, where a house is destroyed, often figuratively, by a single person. Mouse Wreckers was nominated for the Academy Award for Best Animated Short Film for 1948, but lost to The Little Orphan, a Tom and Jerry cartoon which was the fifth Oscar (of seven) given to the cat and mouse team.

The cartoon was loosely remade as Gopher Broke in 1958 (with the Goofy Gophers and the Barnyard Dawg), and later as the Tom and Jerry cartoon The Year of the Mouse in 1965 (also written by Maltese and directed by co-writer Jones).