The Adventures of Rocky and Bullwinkle is a 2000 American live-action/animated adventure slapstick comedy film directed by Des McAnuff and produced by Universal Pictures, based on the television cartoon series of the same name by Jay Ward. Animated characters Rocky and Bullwinkle share the screen with live actors portraying Fearless Leader (Robert De Niro, who also co-produced the film), Boris Badenov (Jason Alexander) and Natasha Fatale (Rene Russo) along with Randy Quaid, Piper Perabo, Kenan Thompson and Kel Mitchell. June Foray reprised her role as Rocky, while Keith Scott (no relation to original voice actor Bill Scott) voiced Bullwinkle and the film's narrator. It also features cameo appearances by performers including James Rebhorn, Paget Brewster, Janeane Garofalo, John Goodman, David Alan Grier, Don Novello, Jon Polito, Carl Reiner, Whoopi Goldberg, Max Grodenchik, Norman Lloyd, Jonathan Winters and Billy Crystal. The film follows Rocky and Bullwinkle, who are enlisting their help by a young rookie FBI agent named Karen Sympathy to stop Boris, Natasha, and Fearless Leader from taking over the United States.

Released on June 30, 2000, the film underperformed at the box-office, grossing $35.1 million worldwide against its $76 million budget. It received mixed reviews with criticisms toward its writing, plot, and humor while praising the performances, visual effects, and faithfulness to its source material.