Deadpool 2 is a 2018 American superhero film based on the Marvel Comics character Deadpool. It is the sequel to Deadpool (2016) and the eleventh installment in the X-Men film series. The film was directed by David Leitch and written by Rhett Reese, Paul Wernick, and Ryan Reynolds, who stars in the title role alongside Josh Brolin, Morena Baccarin, Julian Dennison, Zazie Beetz, T.J. Miller, Brianna Hildebrand, and Jack Kesy. In the film, Deadpool forms the X-Force to protect a young mutant from the time-traveling soldier Cable.

Plans for a sequel to Deadpool began before the original film's release, and were confirmed in February 2016. Though the original creative team of Reynolds, Reese, Wernick, and director Tim Miller were set to return for the second film, Miller left the project in October 2016 due to creative differences with Reynolds and was soon replaced by Leitch. An extensive casting search took place to fill the role of Cable, with Brolin ultimately cast. Principal photography took place in British Columbia from June to October 2017.

Deadpool 2 premiered at the Leicester Square in London on May 10, 2018, and was released in the United States on May 18 by 20th Century Fox. The film outgrossed its predecessor, earning $785 million worldwide, becoming the ninth highest-grossing film of 2018, the highest-grossing film in the X-Men series, and the highest-grossing R-rated film at the time. The film received positive reviews from critics, with some considering it superior to the first film and praising its humor, cast performances, story, and action sequences, while others criticized its tone, script, and recycled jokes. A PG-13-rated version of the film, titled Once Upon a Deadpool, was released on December 12, 2018, to mixed reviews. Following the acquisition of 21st Century Fox by Disney, Deadpool's film rights were returned to Marvel Studios. A sequel, Deadpool & Wolverine, starring Reynolds and Hugh Jackman and integrating their characters into the Marvel Cinematic Universe (MCU), was released on July 26, 2024, as part of Phase Five of the MCU.