Rampage is a 2018 American science fiction monster film directed by Brad Peyton and loosely based on the video game series of the same name by Midway Games, from a screenplay by Ryan Engle, Carlton Cuse, Ryan J. Condal and Adam Sztykiel. The film stars Dwayne Johnson in the lead role, Naomie Harris, Malin Akerman, Jake Lacy, Joe Manganiello and Jeffrey Dean Morgan. It follows a primatologist who, along with his leucistic western lowland gorilla friend that has become a raging creature with fluctuating size enhancements as a result of a rogue experiment, must stop two other mutated animals.

The film is the third collaboration between Peyton and Johnson, following Journey 2: The Mysterious Island (2012) and San Andreas (2015).

Principal photography began in April 2017 in Chicago. The film was released in the United States on April 13, 2018, by Warner Bros. Pictures. The film grossed over $428 million worldwide and received mixed reviews from critics, with praise for its performances (particularly Johnson and Morgan), action sequences and visual effects, but criticism of its screenplay, pacing and storyline.