Mickey's Mellerdrammer is a 1933 American animated short film produced by Walt Disney Productions and released by United Artists. The title is a corruption of "melodrama", thought to harken back to the earliest minstrel shows, as a film short based on Harriet Beecher Stowe's 1852 anti-slavery novel Uncle Tom's Cabin and stars Mickey Mouse and his friends who stage their own production of the novel. It was the 54th Mickey Mouse short film, and the fourth of that year.

The cartoon shows Mickey Mouse and some other characters dressed in blackface with exaggerated lips, bushy sidewhiskers made out of cotton, and the usual white gloves.