Nothing Sacred is a 1937 American Technicolor screwball comedy film directed by William A. Wellman, produced by David O. Selznick, and starring Carole Lombard and Fredric March with a supporting cast featuring Charles Winninger and Walter Connolly. Ben Hecht was credited with the screenplay based on the 1937 story "Letter to the Editor" by James H. Street, and an array of additional writers, including Ring Lardner Jr., Budd Schulberg, Dorothy Parker, Sidney Howard, Moss Hart, George S. Kaufman and Robert Carson made uncredited contributions.

The lush, Gershwinesque music score was by Oscar Levant, with additional music by Alfred Newman and Max Steiner and a swing number by Raymond Scott's Quintette. The film was shot in Technicolor by W. Howard Greene and edited by James E. Newcom, and was a Selznick International Pictures production distributed by United Artists. The film's opening credits feature distinctive caricatures of the leading actors, as 3d-figurines, and creative artists, as 2d-cartoons, by Sam Berman.

This was Lombard's only feature-length Technicolor film. She stated that this film was one of her personal favorites.