Nodame Cantabile (Japanese: のだめカンタービレ, Hepburn: Nodame Kantābire) is a Japanese manga series written and illustrated by Tomoko Ninomiya. It was serialized by Kodansha in the josei manga magazine Kiss from July 2001 to October 2009. A short series, Nodame Cantabile: Encore Opera Chapter, was serialized in the same magazine from December 2009 to August 2010. The overall chapters were collected in 25 tankōbon volumes. In 2016, a one-shot epilogue chapter was published in the same magazine. It was licensed in North America by Del Rey Manga. The series depicts the relationship between two aspiring classical musicians, Megumi "Nodame" Noda and Shinichi Chiaki, as university students and after graduation.

The series has been adapted as four different television series: as an award-winning Japanese live-action drama that aired in 2006 followed by a sequel television special that aired in January 2008, as an anime series spanning three seasons with the first broadcast in 2007, the second in 2008 and the third in 2010. Two live-action movie sequels to the Japanese television drama, with the same actors, were produced with release dates of 18 December 2009 and April 2010. In addition, several soundtrack albums of classical music have been released, as well as three video games. A South Korean drama live action adaptation aired on the KBS network in 2014.

By March 2015, the manga had over 37 million copies in circulation, making it one of the best-selling manga series of all time. It received the 28th Kodansha Manga Award for best shōjo manga in 2004.