Homicide: Life on the Street is an American police drama television series chronicling the work of a fictional version of the Baltimore Police Department's Homicide Unit. It ran for seven seasons and 122 episodes on NBC from January 31, 1993, to May 21, 1999, and was succeeded by Homicide: The Movie (2000), which served as the series finale. The series was created by Paul Attanasio and based on David Simon's book Homicide: A Year on the Killing Streets (1991). Many of the characters and stories used throughout the show were based on events depicted in the book.

While Homicide featured an ensemble cast, Andre Braugher emerged as a breakout star through his portrayal of Detective Frank Pembleton. The show won TCA Award for Outstanding Achievement in Drama in 1996, 1997, and 1998. It also became the first drama ever to win three Peabody Awards for Drama, those being in 1993, 1995, and 1997. It received recognition from the Directors Guild of America Awards, Humanitas Prize, Q Awards, Writers Guild of America Awards and Primetime Emmy Awards. In 1997, the fifth-season episode "Prison Riot" was ranked No. 32 on TV Guide's 100 Greatest Episodes of All Time.

In 1996, TV Guide named the series "The Best Show You're Not Watching". The show placed #46 on Entertainment Weekly's "New TV Classics" list. In 2007, it was listed as one of TIME magazine's "Best TV Shows of All-TIME." In 2013, TV Guide ranked it #55 on its list of the 60 Best Series of All Time.