Blade: The Series is an American television series created by David S. Goyer for Spike based on the Marvel Comics character Blade. Sharing continuity with New Line Cinema's Blade film trilogy, it was produced by New Line Television in association with Marvel Entertainment. The series takes place after the events of the film Blade: Trinity (2004) and stars Sticky Fingaz (credited as Kirk "Sticky" Jones) as Eric Brooks / Blade, with Jill Wagner, Neil Jackson, Jessica Gower, and Nelson Lee also starring. The two-hour pilot was directed by Peter O'Fallon from a script by Goyer (who wrote the scripts for all three of the original films) and Geoff Johns.

Blade: The Series premiered on June 28, 2006, and aired for one season, concluding on September 13, 2006. The show received mixed reviews from critics, who praised the action scenes while criticizing a large number of clichés, as well as the absence of Wesley Snipes in the title role.