Scream Queens is an American satirical dark comedy slasher television series that aired on Fox from September 22, 2015, to December 20, 2016. The series was created by Ryan Murphy, Brad Falchuk, and Ian Brennan and produced by Murphy, Falchuk, Brennan, and Alexis Martin Woodall, and by 20th Century Fox Television, Ryan Murphy Productions, Brad Falchuk Teley-vision, and Prospect Films. The first season stars an ensemble cast consisting of Emma Roberts, Skyler Samuels, Lea Michele, Glen Powell, Diego Boneta, Abigail Breslin, Keke Palmer, Oliver Hudson, Nasim Pedrad, Lucien Laviscount, Billie Lourd, and Jamie Lee Curtis, with Niecy Nash, Ariana Grande, and Nick Jonas in supporting roles. It takes place at the fictional Wallace University, and was filmed at Tulane University in New Orleans, Louisiana. It follows sorority Kappa Kappa Tau (KKT) which is targeted by a serial killer using the university's Red Devil mascot as a disguise.

On January 15, 2016, Fox renewed the series for a second season, which premiered on September 20, 2016. Roberts, Michele, Powell, Breslin, Palmer, Hudson, Lourd, Nash, and Curtis reprised their roles from the first season, while John Stamos, Taylor Lautner, James Earl III, and Kirstie Alley were added to the cast. Instead of a university, the second season was set in a hospital, and was produced in Los Angeles, California.

The show was canceled on May 15, 2017, after two seasons. In May 2020, Murphy confirmed that he is working on a third season of the series.