Lucky Louie is an American television sitcom created by Louis C.K., which aired on HBO for one season in 2006. As the show's creator, writer and executive producer, C.K. also starred as the eponymous central character, a part-time mechanic at a muffler shop.

A first for HBO, Lucky Louie was filmed before a live studio audience, in a multiple-camera setup. Inspired by Norman Lear's sitcoms, the show depicts the life of an average working class family while using spartan sets and wardrobe. Dealing with a range of topics including sex and racism, the series uses considerable adult language and featured guest stars best known as stand-up comedians, including Jim Norton, Laura Kightlinger, Nick DiPaolo, Todd Barry and Rick Shapiro.

HBO ordered 12 episodes, which aired during the 2006 summer season, as well as eight scripts for a second season, before canceling the show in September 2006 for numerous reasons ranging from the nature of the show to network economic pressure.