Spiff and Hercules is a French comic strip titled featuring an anthropomorphic brown-yellow dog named Spiff and a black-white cat named Hercules, who, despite being best friends, are constantly fighting in a friendship/hate relationship. The character Spiff was created by José Cabrero Arnal for the French Communist Party newspaper L'Humanité on 28 March 1948 and the cat Hercules was introduced two years later. The characters' nemesis is Krapulax, who despite his infant-like features always has a diabolical plot in store.Spiff later got his own magazine Pif Gadget, which was very popular as not only did it include several different comic strips, but offered a toy gadget in each issue. He was also the magazine's mascot. Hercules also got his own version of Spiff's magazine, this one called Super Hercules, but his magazine was more joke-oriented. A series of 65 26-minute animated cartoons featuring the characters was produced in 1989 by Europe Images/M5 in France. Each program consisted of two episodes. United Kingdom television station Channel 4 aired the series in 1993.

The adventures of Spiff also appeared as Spiff and Hercules in English translation in the British communist newspaper the Daily Worker (later The Morning Star) until the mid-1970s.