Daniel Boone is an American action-adventure television series, starring Fess Parker as the frontiersman Daniel Boone, that aired from September 24, 1964, to May 7, 1970, on NBC for 165 episodes, and was produced by 20th Century Fox Television, Arcola Enterprises, and Fespar Corp. Ed Ames co-starred as Mingo, Boone's Cherokee friend, for the first four seasons of the series. Albert Salmi portrayed Boone's companion Yadkin in season one only. Country Western singer-actor Jimmy Dean was a featured actor as Josh Clements during the 1968–1970 seasons. Actor and former NFL football player Rosey Grier made regular appearances as Gabe Cooper in the 1969 to 1970 season. The show was broadcast "in living color" beginning in fall 1965, the second season, and was shot entirely in California and Kanab, Utah. The show was highly fictionalized with very little historical accuracy.

An earlier television series based on Daniel Boone appeared on the Walt Disney Presents anthology in 1960, with Dewey Martin as Boone.